Post by Admin on Jul 20, 2024 2:28:53 GMT
See this link www.facebook.com/reel/1568914776986656
Watch this term "trans-genetic plants"
Edible vaccines may reduce the burden of diseases like hepatitis and diarrhoea, particularly in the developing world.
Minor concerns:
1) Consistency of dosage
2) stability of vaccine in fruits not known
3) getting the right does from a plant is tedious
4) which plant offers long term preservation?
Watch this video link: youtu.be/8n4hONDoSSc
Watch this video link : youtu.be/sgS8S2o0DaU
Plants designed to mimic the virus particle
Safeguard against emerging health affects
1) Medicago synthesize the gene of interest
2) Allow bacteria make the viral product
3) Submerge the leaves into water with bacteria
4) Especially interested in poor countries, help with disease
Notice: Medicago gets the GM sequence in bacteria, then soak leaves into the bacteria water, sucking out air to get the water into the leaves with bacteria and than allow leaves to grow the GM product before harvesting the product and getting it ready as a dose for humans to eat.
Edible vaccines: Scientists studying potential of leafy greens as homegrown 'mRNA factories'
By manipulating plants on a micro-scale, a team of scientists led by Juan Pablo Giraldo, an associate professor in University of California, Riverside’s Department of Botany and Plant Sciences, is putting a novel spin on the concept of food as remedy by developing the means for people to grow their own edible mRNA vaccines.
Companies such as Medicago, headquartered in Quebec City, are using plant-based technologies to research and develop possible vaccines for COVID-19, influenza and other diseases. What makes this project unique, though, is that it could potentially give anyone the power to make their own edible vaccine without specialized facilities or expensive infrastructure (or cold chain shipping and storage, like conventional mRNA vaccines).
That we needed to give this a chance and see if it works,” says Giraldo. “We may need mRNA (COVID-19) vaccines for a while, and I’m sure mRNA vaccines are here to stay for all applications.”
It could take several years to show proof of concept in lettuce and spinach crops, Giraldo explains. Their goal is to have the same levels of mRNA in a single plant as in one dose of a conventional shot: “We want one plant to vaccinate one person.”
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healthfeedback.org/claimreview/tennessee-house-bill-hb1894-isnt-evidence-vaccines-present-food-grocery-stores-edible-vaccines-remain-hypothetical/
Tennessee House Bill HB1894 isn’t evidence that vaccines are present in food at grocery stores; edible vaccines remain hypothetical for now
: Research on how to introduce vaccines in edible vegetables is ongoing but still in the early stages. No vegetables containing human vaccines are currently approved or available to the public.
: Researchers have “already perfected the ability to put human vaccines” into certain foods “right now”; grocery vegetables might contain human vaccines
On 21 February 2024, the Tennessee House of Representatives passed a bill (HB1894) on food labeling sponsored by lawmaker Scott Cepicky. The bill “prohibits the manufacture, sale, or delivery, holding, or offering for sale of any food that contains a vaccine or vaccine material unless the food labeling contains a conspicuous notification of the presence of the vaccine or vaccine material in the food”.
The voting was preceded by a hearing in which Cepicky laid out his argument supporting the need for this legislation. Video clips of the hearing went immediately viral on Instagram, Twitter, and TikTok, where many interpreted the discussion as evidence that edible vaccines were already or about to be introduced into the market.
Some social media users suggested that these products were a way to get everyone vaccinated against COVID-19. Others seized the opportunity for promoting “detox” products and supplements to prevent the alleged adverse effects of these vaccines.
Some linked the bill with earlier claims about mRNA COVID-19 vaccines being sneaked into the food supply through vaccinated livestock and genetically modified plants. Health Feedback and other fact-checking organizations reviewed these claims in 2023 and found them to be false.
Likewise, Cepicky’s speech during the hearing contains inaccuracies and is misleading. Vegetables and fruits in grocery stores don’t contain vaccines, and there is no evidence that they will any time soon, as we will show in this review.
Edible vaccines are still in early development
Edible vaccines are plants such as fruits and vegetables that are genetically modified to produce selected genes from harmful microorganisms. The resulting transgenic plants produce the proteins of interest and, when eaten, can generate an immune response in the person just like a traditional vaccine would do.
Because they are easy to produce, administer, and store, edible vaccines offer many potential advantages over traditional vaccines. For example, this technology can be particularly useful in developing countries, where challenges related to refrigeration during vaccine storage and transportation greatly limit access to vaccination.
But contrary to what Cepicky claimed, this technology “won’t be available for human use anytime soon,” Juan Pablo Giraldo, the project leader, told USA Today in 2021. “This research will take a couple of years to show proof of concept of the technology,” Girlando explained. And even after that, he remarked that “it will need more studies and several more years for people to use leafy greens as mRNA vaccine factories”.
We couldn’t find any information about a project developing edible vaccines in tomatoes at this institution. However, similar research was published in February 2024 by a group of researchers in Uzbekistan[3]. The researchers developed transgenic tomatoes that produced part of the spike protein of SARS-CoV-2.
The vaccine, called TOMAVAC, generated an immune response in mice and in 14 healthy adults.
Grocery vegetables currently don’t contain vaccines, and such food vaccine products haven’t been authorized by regulatory agencies in any country. Even if edible vaccines become a reality, they would be subject to drug regulations and therefore unlikely to be distributed in supermarkets and grocery stores.
ROB: How do we know such GM products are not already in the food chain? Can you trust the safety of GM products?
geneticliteracyproject.org/2020/05/08/gmo-tomato-as-edible-covid-vaccine-mexican-scientists-work-to-make-it-a-reality/
GMO tomato as edible COVID vaccine? Mexican scientists work to make it a reality
At the time I write these lines, there are already more than 3.6 million people reportedly infected by the COVID19 pandemic and some 252,000 deaths globally. In the US, which has the world’s highest rate of infection, COVID-19 deaths have surpassed deaths from cancer, coronary heart disease and even influenza/pneumonia in just the few months since the novel coronavirus arrived.
This critical situation has led the entire world to embark on a real race to develop a vaccine that immunizes the population against this new strain of coronavirus, which apparently emerged in the autumn of 2019 in China. So far, more than 100 vaccines are being investigated for COVID-19 by universities, public research centers and especially private companies. Some are already under clinical trial.
The most widely used plant is Nicotiana benthamiana, a close relative of tobacco, due to its biomass, easy laboratory management and rapid growth. But scientists have also worked with other crops, such as lettuce, carrots, potatoes, rice, tomatoes and corn, among others.
Companies already mentioned are working on COVID-19 plant-based antigens by expressing VLPs in GM tobacco. One of them is Medicago, whose CEO claimed the Canadian company would be able to manufacture “10 million doses per month” if its innovative production method and clinical trials obtain US Food and Drug Administration (FDA) approval.
On the other hand, the American company Kentucky Bioprocessing is using a fast-growing GM tobacco of its own and publicly stated that it is already conducting preclinical tests and possesses the ability to manufacture up to three million doses per week.
A root problem for edible vaccines is the popular misconception still ingrained in many people that GM crops “are harmful to health or the environment,” despite thousands of studies and reviews, public statements from more than 250 scientific/technical institutions that corroborate its safety and more than two decades of consuming GM crops with no reported adverse effects.
www.sciencealert.com/review-of-6000-studies-over-two-decades-delivers-its-verdict-on-GMO-corn-safety
A Review of 6,000 Studies Over Two Decades Delivers Its Verdict on GMO Corn
From monikers like "Frankenfoods" to general skepticism, there has been a variety of biased reactions to these organisms, even though we as a species have been genetically modifying our foods in one way or another for approximately 10,000 years.
Mycotoxins, chemicals produced by fungi, are both toxic and carcinogenic to humans and animals. A significant percentage of non-GM and organic corn contain small amounts of mycotoxins. These chemicals are often removed by cleaning in developing countries, but the risk still exists.
GM corn has substantially fewer mycotoxins because the plants are modified to experience less crop damage from insects. Insects weaken a plant's immune system and make it more susceptible to developing the fungi that produce mycotoxins.
In their analysis, the researchers stated that this study allows us "to draw unequivocal conclusions, helping to increase public confidence in food produced with genetically modified plants".
ROB: It is claimed GM food is safe? Such food lacks fungi and bacterial presence? It may well be absent because the GM food is alien to fungi and bacteria. In my humble opinion the presence of bacteria spoiling food means the food is healthy. A lack of fungi means the food is not healthy.
A central challenge is to continue delivering this information, especially to the public and law-makers in developing countries, at pivotal moments, such as when we see that new “plant-based” technologies are making their niche in other fields, such as revolutionary lab-meat.
Will we tell our grandchildren and great-grandchildren stories from the past of painful injections given to us when we were children? Will they live in a future where a couple of lyophilized carrot and lettuce capsules will immunize them against all the killer pathogens of the 19th, 20th and 21st centuries? Or will a delicious vaccine-tomato salad be enough to protect them against some new virulent strain that doesn’t yet exist?
Perhaps this race against time and the urgency of finding a viable vaccine for COVID-19 will enable GM plants to save millions of lives and clear their reputations, unfairly stained and demonized by fear and disinformation, once and for all.
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www.acsh.org/news/2022/03/01/plant-based-vaccines-medicagos-covid-shot-leads-way-16156
Plant-Based Vaccines? Medicago's COVID Shot Leads the Way
Just under two years ago, Canadian biotech firm Medicago began developing a plant-based COVID-19 vaccine.
In the recently published clinical trial results, Medicago's vaccine, “Covifenz,” was 71 percent effective against infection by any SARS-CoV-2 variant and 75 percent against the delta variant. The trial began before omicron began spreading around the world. However, Health Canada announced that “preliminary and exploratory data” from the ongoing study show that the vaccine generates antibodies for omicron and its subvariants.
More than 80 percent of Canadians have received two doses of an approved or authorized COVID-19 vaccine, so COVIFENZ isn't a game-changer at this juncture. The new shot is still an important milestone, though, largely because producing vaccines is expensive and time-consuming. We've been making most flu shots the same way for 70 years, mass-producing candidate vaccine viruses in chicken eggs because we didn't have a better alternative until recently. As we discussed in December, mRNA-based vaccines could alleviate some of the existing production issues, and plant-based shots could do the same.
Plants need nothing more than light, water, soil, and inputs like fertilizer to grow, which means they can be used as relatively inexpensive bioreactors to produce the antigens that go into vaccines. Scaling this production process is easier because it only requires more growing areas, greenhouses or fields, instead of specialized cell culture growth media and actual bioreactors.
Medicago's approach to vaccine development is an excellent example. Scientists synthesize genetic material from a virus, say SARS-CoV-2, and insert it into a soil bacterium (agrobacterium tumefaciens) that efficiently infects plant cells. The transformed plants produce virus-like particles (VLPs) as they grow. The VLPs are then harvested, purified, and used to make vaccines that stimulate neutralizing antibody and cellular immune responses to the spike antigen in the case of SARS-CoV-2. The best part may be this can be done quickly. Medicago had a COVID vaccine candidate ready in March 2020, less than a month after the company gained access to the virus's genome.
Rob" How did Medicago get a plant vaccine ready within a month of COVID if they were not already working on the technique? Do they understand the COVID was just snake venom, and nothing viral about the disease at all?
Given AI world we live in now, how could we prove anything to be true?
I see a future where to only way forward is to entirely grow your own food from your own garden using your own soil and thus your own seeds known factors you know to be healthy. Free natural food. Not genetically modified, by humans pretending to be a god, trans-food. But natural food designed and made by the bigger God we trust.